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  • 1
    ISSN: 1432-1238
    Keywords: Complications ; Pulmonary embolism ; Pregnancy ; Thromboembolic disease ; Thrombolytic therapy ; Recombinant tissue type plasminogen activator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a patient with massive pulmonary embolism and circulatory shock during pregnancy (31 st gestational week) and preterm labour who has been successfully treated with recombinant tissue type plasminogen activator. Thrombolysis was performed using 10 mg·h−1 over 4 h followed by 2 mg·h−1 for 1 h 30 min resulting in complete resolution of cardio-respiratory symptoms. Except for slight bleeding from one puncture site no complications occurred. At 48 h after the end of thrombolytic therapy the patient was delivered spontaneously of a male preterm healthy infant. The relevance of this new thrombolytic agent in the treatment of massive life-threatening pulmonary embolism during pregnancy is discussed.
    Type of Medium: Electronic Resource
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