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  • Triglyceride  (2)
  • [abr] BCECF; 2',7'-bis(carboxyethyl)-5,6-carboxy-fluorescein  (2)
  • cholesterol  (2)
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 176 (1991), S. 639-644 
    ISSN: 0006-291X
    Keywords: [abr] BCECF; 2',7'-bis(carboxyethyl)-5,6-carboxy-fluorescein ; [abr] MIA; 5-(N-methyl-N-isobutyl)amiloride ; [abr] pH"1; cytosolic pH ; [abr] pH"o; extracellular pH
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 176 (1991), S. 639-644 
    ISSN: 0006-291X
    Keywords: [abr] BCECF; 2',7'-bis(carboxyethyl)-5,6-carboxy-fluorescein ; [abr] MIA; 5-(N-methyl-N-isobutyl)amiloride ; [abr] pH"1; cytosolic pH ; [abr] pH"o; extracellular pH
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 61 (1983), S. 1163-1170 
    ISSN: 1432-1440
    Keywords: Triglyceride ; Cholesterol ; Very low density Lipoproteins ; Synthesis ; Secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The liver is the junction of several interorgan metabolic cycles which are essential for the homeostasis of mammalian metabolism. Two of these are described in greater detail and their role in control of lipid metabolism will be presented. The fatty acid-triglyceride cycle is of particular importance for our understanding of the mechanisms governing serum lipid levels. This is due to the fact that the lipoprotein secreted by the liver in the course of this metabolic cycle — very low density lipoprotein — has a relatively long half-life in the plasma compartment. Data have been collected from the literature to show that different nutritional and pharmacological stimuli affecting serum lipid levels do so by interfering with the rate of very low density lipoprotein input into the plasma compartment. The enterohepatic circulation of steroids is another cycle which contributes to control of lipid metabolism. Data are presented which show that bile acids, the major steroids circulating in this cycle, exert direct feedback control of hepatic cholesterol synthesis. This characteristic of bile acids may explain why certain bile acids, when given orally, reduce serum cholesterol levels. Several clinical and experimental observations suggest a close relation between bile acid and triglyceride metabolism. It is characterized by an inverse relation between bile acid pool size and serum triglyceride levels. Moreover, a reduction of the bile acid pool size is accompanied by an enhanced hepatic fatty acid and triglyceride synthesis and secretion into blood. The molecular basis and physiological significance of these observations have still to be explored. Special emphasis is put on the advantage of monolayer cultures of liver cells which had to be used in order to reach much of the experimental evidence outlined herein. This cellular model endowed with the physiology and phenotype of the normal adult liver cell is particularly suited to the study of long-term regulation of metabolism.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1436-6215
    Keywords: pig ; dietary protein ; intestine ; bile acids ; cholesterol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung In der vorliegenden Studie werden quantitative und qualitative Unterschiede im Gehalt an Gallensäuren und Cholesterin beschrieben, die im Dünndarm von Miniaturschweinen nach Diäten beobachtet wurden, die entweder Casein oder Sojaproteinisolat enthielten. Die intestinale Gesamtmenge an Gallensäuren war signifikant höher, wenn Sojaproteinisolat gefüttert worden war. Wurde das Protein als einzige Komponente verfüttert, so lagen die Werte bei 4.51±0.39 mmol, während die Caseingruppe 2.43±0.08 mmol aufwies. Wurde das Protein als Teil einer semisynthetischen Diät gegeben, waren die Werte für die Sojagruppe 6.44±1.04 mmol und für die Caseingruppe 3.95±0.39 mmol. Bei der Caseingruppe lagen die prozentualen Anteile an der Gesamtmenge der Gallensäuren im Dünndarm bei 39.6 % Hyocholsäure, 31% Hyodeoxycholsäure und 27.6% Chenodeoxycholsäure. Die Tiere, die Sojaproteinisolat bekamen, hatten in der Tendenz mehr sekundäre Gallensäuren. Das Chymusfrischgewicht im Dünndarm lag in der Sojagruppe um 63 % über dem der Caseingruppe. Unter allen experimentellen Bedingungen wurde eine enge Beziehung zwischen dem Gehalt an Chymus und Gallensäuren im Dünndarm beobachtet. Die Sojagruppe wies in der Tendenz höhere Mengen an Gallensäuren im distalen Jejunum auf. Die Soja- und Caseingruppe wiesen keine Unterschiede im Cholesteringehalt des Dünndarms auf.
    Notes: Summary This study reports quantitative and qualitative differences in intestinal bile acids and cholesterol in miniature pigs following dietary casein or soy protein isolate. The total amount of bile acids in the small intestine was significantly higher when soy protein isolate was fed in comparison to casein. The values were (mean±SEM) 4.51 ±0.39 mmol and 2.43±0.08 mmol, respectively, when the proteins were given as the sole component of the diet. When the proteins were given as part of a semipurified diet, these values were 6.44±1.04 mmol and 3.95±0.39 mmol, respectively. Hyocholic acid amounted to 39.6%, hyodeoxycholic acid to 31 %, and chenodeoxycholic acid to 27.6% of total bile acids in the small intestine when casein was fed. The soy-fed animals tended to have more secondary bile acids. The total small bowel chymus content, on a wet weight basis, was 63 % higher in the soy group. In all experimental conditions studied, there was a close correlation between small bowel chyme content and bile acid content. The distribution of bile acids in the small intestine showed that the soy fed animals tended to have more bile acids in the distal parts of the jejunum. The intestinal cholesterol contents were not significantly different between dietary groups.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1436-6215
    Keywords: cholesterol ; triglycerides ; lipoproteins ; ω 3 fatty acids ; Cholesterol ; Triglyceride ; Lipoproteine ; ω-3-Fettsäuren
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung In einem Kurzzeit-Experiment wurde an gesunden, normolipidämischen Probanden geprüft, ob durch einen mäßig hohen Fischverzehr der Gehalt an Plasma- und Lipoproteinlipiden gesenkt werden kann. 8 Teilnehmer aßen eine Woche lang täglich 100 g Makrele (entsprechend etwa 2,5–3 g ω-3-Fettsäuren). Die Triglycerid-Konzentrationen im Plasma und in den VLDL und LDL waren nach der Fischdiät um 40, 46,7 und 38,5 % niedriger als zu Beginn des Experiments. Die Plasmacholesterol-Konzentration war nur geringfügig erniedrigt, das Verhältnis HDL/Gesamt-Cholesterol aber signifikant erhöht. Die Studie zeigt, daß eine moderate Steigerung des Fischverzehrs bei gesunden, normolipidämischen Probanden innerhalb einer Woche — selbst auf der Basis einer nicht strikt kontrollierten Diät — die Lipidspiegel verändern kann.
    Notes: Summary The effect of mackerel consumption on plasma and lipoprotein lipid concentrations was studied in a seven-day experiment in eight healthy, normolipidemic subjects. Participants ate about 100 g mackerel (corresponding to about 2.5–3 g ω3 fatty acids daily. The mean triglyceride concentrations in total plasma, VLDL, and LDL were significantly reduced by 40, 46.7, and 38.5 % respectively after fish consumption. There was also a small (non-significant) reduction of plasma cholesterol and a (significant) increase of the ratio of HDL/total plasma cholesterol. These data show that a moderately increased intake of ω-3 fatty acids by fish food can change lipid characteristics in healthy normolipidemic individuals within a short-time period, even on a free diet.
    Type of Medium: Electronic Resource
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