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Chronic renal failure in methylmalonic acidaemia (1989)

Walter, J. H. ; Michalski, A. ; Wilson, W. M. ; [et al.]

Springer

European journal of pediatrics 148 (1989), S. 344-348

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ISSN: 1432-1076

Keywords: Methylmalonic acidaemia ; Chronic renal failure ; Tubulo-interstitial nephritis

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The renal function of 12 patients with non vitamin B12 responsive methylmalonic acidaemia has been investigated. Eight patients had reduced glomerular filtration rates, but the plasma creatinine concentration was only raised in those with values of less than 40ml/min per 1.73m2 surface area. The reduction in glomerular filtration was a function of the age and the severity of the disease. Plasma urate concentrations were increased in four patients but this may be secondary to the renal disease rather than its cause.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00444131

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