ISSN:
1432-1246
Keywords:
Toluene
;
Urinary hippuric acid
;
Energetical load
;
Aliphatic hydrocarbons
;
Heliorotagravure printing
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The influence of a number of factors possibly affecting the relation between urinary hippuric acid excretion and the exposure level to toluene was studied in a population of heliorotagravure printers. It was observed that the hippuric acid excretion rates, after 4 h and 8 h from the onset of the exposure, were in better agreement with the average toluene concentrations in work room air than either the urinary metabolite concentrations alone or corrected for urine density. Apart from differences in exposure level, a substantial proportion of the interindividual variability in hippuric acid excretion could be explained by differences in energetical load during the exposure. It was thereby not possible to elucidate the full extent to which this factor influences the metabolite excretion. In good agreement with previous experimental findings, the hippuric acid excretion rate apparently does not depend on the time of urine sampling during the exposure, provided that at least 4 h have elapsed from the onset.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00386743
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