ISSN:
0009-2940
Keywords:
Steroids
;
Chiral amino alcohols
;
Copper(II) salicylideneimine complexes
;
X-ray analysis
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The steroidal 16β-salicylideneimino-17β-hydroxy compound 1, synthesized from the corresponding 16β, 17β-amino alcohol, served as a new tridentate chiral ligand for Cu2+-complexation. The X-ray data for 1 and for two dimeric copper complexes 2 and 3 are presented and discussed. Using copper(II) acetate for complexation, dideprotonation of 1 is observed. The neutral complex 2 obtained is characterized by a central planar four-membered copper - oxygen ring. The cycloaliphatic 17β-oxygen anions are bridging atoms; the copper ions are tetracoordinated. Reaction of 1 with copper(II) perchlorate gave only monodeprotonation of the phenolic groups. These oxygen anions are now the bridging atoms; furthermore the two copper ions are bridged by a perchlorate anion. Thus the central four-membered ring is folded (22°), and the copper ions are hexacoordinated (binding of a molecule of water). The crystal lattices of 2 and 3 are also quite different.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19961291216
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