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  • 1
    ISSN: 1573-2622
    Keywords: adaptation ; aqueous humor ; electroretinogram ; intraocular fluids ; osmolarity ; vitreous humor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In experiments by Yoneyama et al. (1985) a hypertonic perfusing solution was used to record the c-wave from the isolated chick retina. We investigated whether the chick retina was surrounded by such hypertonic liquids. The following results were found: (1) the osmolarity of the subchoroidal humor was markedly higher than that of fluids from other areas of the eye; (2) the relative difference in osmolarity between both sides of the retina was 110–170 mOsmol in the light-adapted condition, whereas it was about 270 mOsmol in the dark-adapted condition; and (3) in the dark-adapted state the volume of the subchoroidal humor decreased about 40% but increased in osmolarity about 30–40%, whereas osmolarity of the subviteous humor decreased about 15–20 mOsmol. Results suggest the presence of an inward-directed pump mechanism for watersoluble components in the retina in addition to the proposed outward-directed pump mechanism of the pigment epithelium. The inward-directed pump may be more active in the dark-adapted state.
    Type of Medium: Electronic Resource
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