ISSN:
1432-1041
Keywords:
ethoxyresorufin 0-deethylase
;
alcoholic liver disease
;
environmental carcinogens
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary We have investigated the effect of alcoholic liver disease (ALD) on the metabolism of 7-ethoxycoumarin 0-deethylase in human liver microsomes. EROD activity was significantly reduced in tissue from ALD patients who smoked, compared to smoking controls. A similar trend was seen in non-smokers. These results have implications for the metabolism of environmental carcinogens.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02455988
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