ISSN:
1573-8744
Keywords:
dialysis
;
drugs
;
renal failure
;
gentamicin
;
kanamycin
;
tobramycin
;
amikacin
;
ethambutol
;
procainamide
;
flucytosine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Hemodialyzer clearance studies have been undertaken on the following drugs: gentamicin, kanamycin, tobramycin, amikacin, ethambutol, procainamide, and flucytosine. The following hemodialyzers were tested: Dow model 4, Kiil, Travenol UF II, and the Extracorporeal EX-03. The studies were predominantly undertaken in vitro,permitting direct comparison between drug clearances on the same dialyzer. Protein binding studies for gentamicin, kanamycin, procainamide, and ethambutol are also reported. Nomograms to facilitate the prediction of drug dosage regimens in dialysis patients are included.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01062830
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