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New technique in optical resolutions (1994)

Ács, Mária ; Mravik, András ; Fogassy, Elemér ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Chirality 6 (1994), S. 314-320

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ISSN: 0899-0042

Keywords: amphetamine ; distillation method ; clathrate ; optical activation of bases ; Chemistry ; Organic Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: The present paper illustrates the development of an advanced technique in optical resolution. Both of the amphetamine enantiomers can be obtained by a two-step distillation in nearly quantitative yield without any loss of the resolving agent. It is proved that the second-order interactions (H-bond) are sufficient for separation of enantiomers by distillation. © 1994 Wiley-Liss, Inc.

Additional Material: 2 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/chir.530060415

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