Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Ultrastructure of Nuclear Compartment in Cardiomyocytes during Regenerative and Plastic Insufficiency of the Myocardium (2000)
    Springer
    Bulletin of experimental biology and medicine 130 (2000), S. 1196-1201 
    Details
    ISSN: 1573-8221
    Keywords: anthracycline antibiotics ; plastic myocardium insufficiency ; cardiomyocyte nuclei and nucleoli ; ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We studied ultrastructure of nuclear compartment in cardiomyocytes during regenerative and plastic insufficiency of the myocardium induced by anthracycline antibiotic daunomycin. A peculiarity of ultrastructural organization of cardiomyocyte nuclei under these conditions is almost complete disappearance of the heterochromatin lumps. The earliest changes in nucleoli under conditions of disturbed DNA-dependent RNA synthesis are segregation of the granular and fibrillar nucleolonema components. Deep alterations in the nucleoli manifested by fragmentation and annulation correlate with pronounced changes in cardiomyocytes ultrastructure, intensive lysis of the myofilaments, reduction of the organelles, and enhanced autophagocytosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1017544304633
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Focal Degradation of Cytoplasmic Organelles in Cardiomyocytes during Regenerative and Plastic Myocardial Insufficiency (2000)
    Springer
    Bulletin of experimental biology and medicine 130 (2000), S. 1190-1195 
    Details
    ISSN: 1573-8221
    Keywords: anthracycline antibiotics ; regenerative and plastic myocardial insufficiency ; cardiomyocyte ; cytoplasm ; ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Focal degradation of cardiomyocyte ultrastructures and cytoplasm, their sequestration, and autophagy were found in Wistar rats with daunomycin-induced regenerative and plastic myocardial insufficiency starting from day 1 after cytostatic treatment. These changes were morphologically manifested in the formation of myelin-like structures, autophagosomes, and secondary lysosomes. Sequestration and partial autophagy of the cytoplasm in cardiomyocytes with diminished or blocked protein synthesis reflect cell regression or involution directed to the adjustment of the cytoplasm volume to functional state of the nucleus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1017592220563
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...