Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Morphological manifestations of anthracycline cardiomyopathy in the ventricular myocardium of rats (1987)
    Springer
    Bulletin of experimental biology and medicine 104 (1987), S. 1018-1022 
    Details
    ISSN: 1573-8221
    Keywords: anthracycline cardiomyopathy ; plastic insufficiency of the heart ; right and left ventricular myocardium ; cardiomyocyte ultrastructure ; morphometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00841928
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Peculiarities of Intracellular Regeneration of Cardiomyocytes during Plastic Myocardial Insufficiency (2000)
    Springer
    Bulletin of experimental biology and medicine 130 (2000), S. 1011-1016 
    Details
    ISSN: 1573-8221
    Keywords: anthracycline cardiomyopathy ; SHR rats ; plastic myocardial insufficiency ; cardiomyocytes ; intracellular regeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We performed morphological assay of the myocardium in Wistar rats with anthracycline cardiomyopathy and SHR rats with genetically determined arterial hypertension causing hypertrophic cardiomyopathy. Both disorders were accompanied by a decrease in protein synthesis and development of plastic cardiomyocyte insufficiency. Electron microscopy revealed peculiarities of intracellular regeneration of cardiomyocytes. We observed disorientation of newly formed myofibrils lying between preserved myofibrils. These myofibrils were positioned perpendicular or at angle to the long axis of muscle fibers, or extended from the Z line (in a fan-like manner) crossing each other. Regeneration disturbances also included excessive elongation of myofibrils. These abnormalities of myofibril regeneration were related to changes in transcription and translation in cardiomyocytes, due to DNA damages caused by cardiotoxic doses of rubomycin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1002886428718
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Apoptosis of Cardiomyocytes as Extreme Manifestation of Regeneration and Plastic Insufficiency of Myocardium (2000)
    Springer
    Bulletin of experimental biology and medicine 130 (2000), S. 903-907 
    Details
    ISSN: 1573-8221
    Keywords: anthracycline cardiomyopathy ; regeneration and plastic myocardium insufficiency ; cardiomyocytes ; absolute number of cardiomyocytes ; apoptosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Alkaline dissociation of the myocardium from rats with modeled anthracycline cardiomyopathy revealed decreased absolute number of cardiomyocytes, disturbances in their intracellular regeneration, although no sings of necrosis were observed. Regeneration and plastic insufficiency of the myocardium due to structural changes in the nuclei and disturbances in myofibril reproduction resulting from selective suppression of synthesis of contractile proteins in the cardiomyocytes leads to the death of up to 30% cardiomyocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1015386800781
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...