ISSN:
0947-6539
Keywords:
asymmetric syntheses
;
epothilones
;
macrolides
;
natural products
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Members of a new class of macrolide - the so-called epothilones (1) - showing a taxol-like biological activity have recently been isolated. A convergent approach to 1 is presented, and the asymmetric syntheses of the three key intermediates 3, 4, and 8 are reported.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chem.19960021121
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