ISSN:
1572-8900
Keywords:
γ-Butyrolactone
;
l-lactide
;
biodegradable polymer
;
hydrolysis
;
ring-opening polymerization
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Energy, Environment Protection, Nuclear Power Engineering
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract Biodegradable polyesters were synthesized by ring-opening copolymerization of γ-butyrolactone (BL) and its derivatives withl-lactide (LLA). Although tetraphenyl tin was the main catalyst used, other organometallic catalysts were used as well.1H and13C NMR spectra showed that poly(BL-co-LLA)s were statistical and that their number-average molecular weights were as high as 7×104. The maximum BL content obtained from copolymerization BL/LLA was around 17%. TheT m andT g values of the copolymers showed a gradual depression with an increase in BL content. NoT m was obtained for the copolymers containing more than 13 mol% BL. The biodegradability of the copolyesters was evaluated by enzymatic hydrolysis and nonenzymatic hydrolysis tests. The enzymatic hydrolysis was carried out at 37°C for 24 h using lipases fromRhizopus arrhizus andR. delemar. Hydrolyses by both lipases showed that an increase in BL content of the copolymer resulted in enhanced biodegradability. Nonenzymatic accelerated hydrolysis of copolymers at 70°C was found to increase proportionally to their exposure time. The hydrolysis rate of these copolymers was considerably faster than that of PLLA. The higher hydrolyzability was recorded for the BL-rich copolymers. The copolymerization of γ-methyl-γ-butyrolactone (MBL) or γ-ethyl-γ-butyrolactone (EBL) with LLA resulted in relatively LA-rich copolymers.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02067454
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