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Activation of brain and kidney Na, K-ATPase in rats during adaptation to cold (1979)

Larionov, N. P. ; Medvedev, L. N. ; Khramenko, S. A.

Springer

Bulletin of experimental biology and medicine 87 (1979), S. 206-207

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ISSN: 1573-8221

Keywords: adaptation ; cold ; Na,K-ATPase ; brain ; kidney

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract During interrupted and prolonged (16 weeks) adaptation of rats to cold the Na,K-ATPase activity in their brain and kidneys is increased by 50–100% with no change in the affinity of the enzyme for ATP. It is suggested that an increase in the power of the triiodothyronine (T3)-dependent sodium pump in the kidneys and of the T3-independent sodium pump in the brain resulting from adaptation enables heat production to be increased during cooling of the animal.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00801777

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