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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 195 (1986), S. 276-280 
    ISSN: 1432-041X
    Keywords: cAMP-analogues ; Sporangia morphogenesis ; HPLC ; Microinjection ; Physarum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Plasmodial cells of the slime moldPhysarum polycephalum become competent for sporulation following a prolonged period of starvation in darkness. Then sporulation can be induced by illumination. Microinjections of the stable (Sp)- and (Rp)-diastereoisomers of adenosine cyclic 3′,5′ monothionophosphate before and during a sensitive period from the start of illumination until 5 h after lead to a significant delay in the sporulation process. Both of the diastereoisomers of cyclic AMP prolong the time for sporangia to form in darkness. However, the (Sp)-diastereoisomer is more effective and causes morphological changes in plasmodia. The experimental data suggest that cyclic AMP is decisively involved in light-induced differentiation in the lower eukaryotoPhysarum polycephalum.
    Type of Medium: Electronic Resource
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