ISSN:
1432-1041
Keywords:
timolol
;
pharmacokinetics
;
pharmacodynamics
;
healthy subjects
;
cardiac infarction patients
;
i.v. therapy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Disappearance pharmacokinetics, pharmacodynamics and general tolerance of i.v. timolol were compared in 12 healthy volunteers and 10 patients with a definite or proven acute myocardial infarction. The drug was administered to the patients immediately on arrival at the hospital after a median delay time of 4 h. Tolerance to the injections was good in both volunteers and patients. The study revealed disappearance pharmacokinetics that were similar in volunteers and patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01061376
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