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  • cardiovascular disease  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of cardiovascular disease on pharmacokinetics (1989)
    Springer
    Cardiovascular drugs and therapy 3 (1989), S. 711-730 
    Details
    ISSN: 1573-7241
    Keywords: cardiovascular disease ; pharmacokinetics ; antiarrhythmics ; inotropics ; betablockers ; diuretics ; antihypertensives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pathophysiologic changes occurring in cardiovascular disease can affect the kinetics of drugs in several different ways. The present review examines these modifications and the underlying mechanisms. The kinetics of specific agents, such as antiarrhythmic, antihypertensive, cardiotonic, and other drugs are considered, and the clinical implications are outlined. The clinician should be aware of these modifications, because they require an adjustment of the dosage regimen. A rational basis for a correct therapeutic choice can be provided by adequate knowledge of these modifications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01857622
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