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  • chronic cardiac sympathectomy  (1)
  • collateral blood flow distribution  (1)
  • intramyocardial collaterals  (1)
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Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Basic research in cardiology 76 (1981), S. 305-312 
    ISSN: 1435-1803
    Keywords: septal artery ; circumflex occlusion ; right cor. occlusion ; collateral blood flow distribution ; collateral pattern
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir untersuchten zwei Modelle des Koronarverschlusses: Dreimonatige Okklusion des Ramus circumflexus und rechte Koronarokklusion. Nach Koronarverschluß fand Kollateralentwicklung in normal aktiven Hunden statt. Kollateralperfusion wurde an einem isolierten Herzpräparat gemessen. Die Resultate erwiesen, daß ein gewisses Schema der Kollateralentwicklung zugrunde liegt. Kollateralperfusion was im allgemeinen zum linken Herzen mit Ramus-circumflexus-Okklusion orientiert und zum rechten herzen mit rechtem Koronarverschluß. Obwohl die Hauptkollateralisierung über epikardiale Kollateralen stattfand, fanden wir aktive intramyokardiale Entwicklung von der Septalarterie in beiden Modellen. Kollateralentwicklung zum Ramus circumflexus nach Verschluß war 6.54mal größer als die zur rechten Koronararterie. Die Resultate deuten auf eine Beziehung zwischen Kollateralwachstum und Größe des ischämischen Gebietes hin.
    Notes: Summary Two models of gradual coronary occlusion (Ameroid method) were compared in this study: 3 months circumflex and 3 months right coronary occlusion. Following coronary occlusion, the collaterals developed in intact, normally active dogs. The collateral flows were assessed in an isolated heart preparation. The results indicated a pattern for collateral development. Collateral flow was directed primarily toward the left heart with circumflex occlusion, and toward the right heart with right occlusion. Although dominant collateralization was via epicardial collaterals, intramyocardial septal collaterals strongly participated in growth development of both models. Collateral growth to the circumflex with circumflex occlusion was 6.54 fold greater than collateral growth to the right coronary artery with right occlusion. The data suggest a relationship between collateral growth and ischemic bed size.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Basic research in cardiology 78 (1983), S. 373-383 
    ISSN: 1435-1803
    Keywords: intramyocardial collaterals ; chronic cardiac sympathectomy ; retrograde blood flow ; coronary collateral circulation ; collateral blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have shown that chronic cardiac sympathectomy reduces coronary collateral resistances. The present experiments in isolated dog hearts delineated the role of intramyocardial collateral channels from the septal (SEP) to the circumflex (CIRC), left anterior descending (LAD), and right (RT) coronary arteries in this phenomenon. In 11 controls and 8 2-wk sympathectomized hearts, a retrograde flow technique was used to determine collateral resistances between the epicardial arteries (CIRC, LAD, RT). Collateral resistances between the CIRC and LAD and between the LAD and RT were 42–68% less in sympathectomized hearts (P〈0.05). Collateral resistances from the SEP to each epicardial artery were determined from retrograde flows simultaneously collected on each epicardial artery when the SEP was the only vessel perfused. Collateral resistances from the SEP to the CIRC and LAD were 51–59% less in the sympathectomized hearts (P〈0.05). Thus, intramyocardial channels from the SEP to the left coronary arteries show reduced resistances after sympathectomy and can provide a substantial portion of the increased collateral flow to these vessels.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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