Digitale Medien
Springer
International journal of peptide research and therapeutics
5 (1998), S. 125-128
ISSN:
1573-3904
Schlagwort(e):
combinatorial chemistry
;
MHC
;
peptidomimetics
;
solid-phase synthesis
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Abstract New ligands for major histocompatibility complex (MHC) class I molecules were prepared using a flexible automated synthesis of oligocarbamates. An efficient solution-phase synthesis was found for Fmoc-amino alcohols which are required as building blocks. The biological activity of the oligomeric peptidomimetics was demonstrated in a stabilizing assay with MHC class I presenting cells.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1023/A:1008821817913
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