ISSN:
0942-0940
Keywords:
Subarachnoid haemorrhage
;
early aneurysm clipping
;
cyclosporine A
;
neurological outcome
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In the present study we found that the neurological outcome in patients anaesthetised for early clipping (up to 72 h after SAH) of a ruptured aneurysm and treated with cyclosporine A was significantly better than the neurological state of control patients without immuno-suppressive treatment. The results justify the presumption that auto-immune reactions are involved in the deterioration of the postoperative neurological state of patients with SAH after rupture of an intracranial aneurysm. Supplementing a standard surgical and pharmacological treatment with cyclosporine A seems to reduce the undesirable neurological consequences of the immunologically, induced vascular disturbance after SAH.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01402450
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