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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 35 (1990), S. 349-352 
    ISSN: 1573-2568
    Keywords: ulcerative colitis ; strictures ; dysplasia ; cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Previous studies have found a widely variable prevalence of dysplasia and cancer in colonic strictures in patients with ulcerative colitis. Consequently, therapeutic recommendations are conflicting. To better assess the prevalence, we reviewed the clinical and pathological findings in all 27 patients with ulcerative colitis complicated by stricture who were entered into our Inflammatory Bowel Disease Registry. A true stricture was defined as a persistant localized narrowing of the colon found on air-contrast barium enema or on colonoscopy. Upon careful review, 12 of 27 patients were found to have transient colonic spasm, not a stricture, and were excluded. The remaining 15 patients with true strictures represented 3.2% of all ulcerative colitis patients in the registry. Strictures were identified at 13.3± 9.9 years following the diagnosis of ulcerative colitis. Eleven patients had multiple strictures that were principally located in the left colon. Of the 15 patients, 11 had dysplasia and two had cancer found on colonoscopic biopsy. Ultimately, six patients had carcinoma found at colonoscopy or colectomy (three modified Dukes' stage A, one stage B, and two stage D). All cancers were at the site of a stricture. These findings indicate that a true colonic stricture in ulcerative colitis is frequently associated with dysplasia and cancer, which can be diagnosed with colonoscopic biopsy. A stricture should be considered a strong risk factor for cancer, requiring intensive colonscopic surveillance. If dysplasia is discovered, or if the stricture cannot be adequately biopsied, consideration should be given to total colectomy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 313-314 (1995), S. 15-20 
    ISSN: 1573-5117
    Keywords: colonization ; rotifers ; zooplankton ; vagility ; dispersal ; metapopulations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Twelve new experimental ponds were constructed identically, filled simultaneously, had similar physical and chemical properties, and were maintained with minimal manipulation. Colonizing zooplankton communities were sampled bi-weekly for one year. Rotifers dominated zooplankton communities in densities, biomass, and species number (47 of 61 observed species were rotifers). Only 14 species were observed in all 12 ponds; 9 were rotifers. Twenty-nine species (26 rotifers) were recorded in 〈-6 ponds. Species with high vagility exhibited greater viability. Ponds differed in zooplankton community composition throughout the year, due to differences in both vagility and viability among colonizing species.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Environmental biology of fishes 58 (2000), S. 157-172 
    ISSN: 1573-5133
    Keywords: generalized additive models ; acoustics ; pelagic ; oceanography ; zooplankton ; North Sea ; abundance ; distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Trends in mean abundance of North Sea Atlantic herring, Clupea harengus, over the period of 1992–1995, were modelled as a function of spatial location and ocean environmental conditions using generalized additive models (GAM). In all four years, the average herring abundance was found to be highest in latitudes around 60.5°N, and decreased with increasing latitude. The thermocline depth had a significant effect on prespawning herring abundance both directly, as a main effect, and indirectly, through its interactive effect with the temperature at 60 m. Average herring abundance was highest in areas having deeper thermocline depths (up to 45 m) and temperatures at 60 m between 9 and 11°C. Prespawning herring abundance was greater in areas of cooler surface waters in the south than in the north. Well-mixed waters and transition zones between frontal and stratified areas having sea surface temperatures mainly between 11 and 12°C and to a lesser extent between 13 and 14°C were associated with the highest herring abundance. Herring appeared to avoid the cold bottom waters in summer. Multiyear GAM analysis revealed consistent environmental preferenda of herring and affirmed further a significant decrease in herring abundance. As herring numbers declined, the population aggregated in the most preferred areas. The inter-relationships of herring and environmental factors across the study period, were similar in their structure and significance, suggesting that preferred areas for location of herring can be reasonably predicted.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-7225
    Keywords: diet ; dysplasia ; mouth neoplasms ; precancerous conditions ; risk factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objectives: Oral epithelial dysplasia (OED) is a histopathologic diagnosis associated with an increased risk of oral cancer. The paper explores the relationship between OED risk and food group intake. Methods: In this case–control study, incident cases of OED were identified through two oral pathology laboratories. Controls, pair-matched 1:1 to cases on age ( ± 5 years), gender, appointment date ( ± 1 year), and surgeon, were identified through the office in which the respective case was biopsied. Exposure data were obtained via a telephone interview and mailed food-frequency questionnaire. cConditional logistic regression was used to obtain odds ratio point estimates. Results: Based upon 87 matched pairs – and after controlling for smoking, drinking, and other potential covariates–there was an apparent inverse relationship between OED risk and the consumption of fruits and vegetables, with the intake of these foods being associated with a strong attenuating effect among smokers. OED risk decreased with increased poultry consumption, but increased modestly with bread/cereal and dairy food intake. Conclusions: This investigation provides evidence that some aspects of diet may be associated with the risk of OED. It also suggests that in oral carcinogenesis the role of diet is not simply one of a late effect.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 287-388 (1998), S. 15-21 
    ISSN: 1573-5117
    Keywords: Rotifera ; zooplankton ; dispersal ; colonization ; wind ; rain ; waterfowl
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Zooplankton, and especially rotifers, have long been thought to be readily dispersed by wind, rain and animals (especially waterfowl). Given that premise, local processes (tolerance to abiotic conditions, biotic interactions) have been the main focus of ecological studies. We tested the premise of high dispersal rates by incubating particulates collected with windsocks and rain samplers at two sites over 1 year. The sites were 80 km apart and differed in proximity to water and surrounding terrain. We also incubated fecal material of wild ducks. Pond sediments were identically incubated as a test of incubation method. Only bdelloid rotifers were collected in wind samples, and only four rotifer species were collected in rain samples: Lecane leontina, Lecane closterocerca, Keratella cochlearis, and a bdelloid. No metazoans were found in incubated duck feces, yet incubated pond sediments yielded 11 rotifer, one copepod, four cladoceran, and three ostracod species. Our results do not support the premise of readily dispersed zooplankton. If zooplankton dispersal is infrequent and limited to few species, a series of other questions should be addressed on processes regulating zooplankton population dynamics and community composition.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 287-388 (1998), S. 207-214 
    ISSN: 1573-5117
    Keywords: zooplankton ; rotifers ; colonization history ; disturbance ; nutrient enrichment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We compared the relative importance of colonization history to other known regulators of freshwater zooplankton assemblages (i.e. disturbance and nutrient enrichment) during this six-month study of initial colonization in artificial freshwater pools. We experimentally manipulated 16 small (1.5 m diameter) pools for permanence (permanent vs. temporary) and resource availability (± nitrogen & phosphorus). Nitrogen and phosphorus were added to high resource level pools in concentrations typical of eutrophic waters, while low resource level pools did not receive added nutrients. Permanent pools were maintained with added tap water and temporary pools dried out naturally for one month. Zooplankton colonization was limited to only 10 rotifers (species of Brachionus, Cephalodella, Lecane, Lepadella, Rotaria, and Trichocerca) and 2 crustaceans. Treatments significantly affected physical-chemical variables, colonization curves (species richness through time), and mean cumulative species number. Results indicate that local conditions (habitat permanence and resource availability) had the greatest effect on zooplankton species richness. However, low species diversity and little treatment effect on species relative abundance patterns suggest that colonization history (dispersal) was also important. Therefore, colonization history and local conditions were jointly responsible for structuring zooplankton assemblages in this study. Colonization history may have lasting effects on zooplankton composition in older, natural systems as well, but may be overlooked at some scales of measurement.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 387-388 (1998), S. 207-214 
    ISSN: 1573-5117
    Keywords: zooplankton ; rotifers ; colonization history ; disturbance ; nutrient enrichment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We compared the relative importance of colonization history to other known regulators of freshwater zooplankton assemblages (i.e. disturbance and nutrient enrichment) during this six-month study of initial colonization in artificial freshwater pools. We experimentally manipulated 16 small (1.5 m diameter) pools for permanence (permanent vs. temporary) and resource availability (± nitrogen & phosphorus). Nitrogen and phosphorus were added to high resource level pools in concentrations typical of eutrophic waters, while low resource level pools did not receive added nutrients. Permanent pools were maintained with added tap water and temporary pools dried out naturally for one month. Zooplankton colonization was limited to only 10 rotifers (species of Brachionus, Cephalodella, Lecane, Lepadella, Rotaria, and Trichocerca) and 2 crustaceans. Treatments significantly affected physical-chemical variables, colonization curves (species richness through time), and mean cumulative species number. Results indicate that local conditions (habitat permanence and resource availability) had the greatest effect on zooplankton species richness. However, low species diversity and little treatment effect on species relative abundance patterns suggest that colonization history (dispersal) was also important. Therefore, colonization history and local conditions were jointly responsible for structuring zooplankton assemblages in this study. Colonization history may have lasting effects on zooplankton composition in older, natural systems as well, but may be overlooked at some scales of measurement.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 387-388 (1998), S. 15-21 
    ISSN: 1573-5117
    Keywords: Rotifera ; zooplankton ; dispersal ; colonization ; wind ; rain ; waterfowl
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Zooplankton, and especially rotifers, have long been thought to be readily dispersed by wind, rain and animals (especially waterfowl). Given that premise, local processes (tolerance to abiotic conditions, biotic interactions) have been the main focus of ecological studies. We tested the premise of high dispersal rates by incubating particulates collected with windsocks and rain samplers at two sites over 1 year. The sites were 80 km apart and differed in proximity to water and surrounding terrain. We also incubated fecal material of wild ducks. Pond sediments were identically incubated as a test of incubation method. Only bdelloid rotifers were collected in wind samples, and only four rotifer species were collected in rain samples: Lecane leontina, Lecane closterocerca, Keratella cochlearis, and a bdelloid. No metazoans were found in incubated duck feces, yet incubated pond sediments yielded 11 rotifer, one copepod, four cladoceran, and three ostracod species. Our results do not support the premise of readily dispersed zooplankton. If zooplankton dispersal is infrequent and limited to few species, a series of other questions should be addressed on processes regulating zooplankton population dynamics and community composition.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 50 (1992), S. 10-19 
    ISSN: 0730-2312
    Keywords: cancer ; dysplasia ; hyperplasia ; prostate ; prostatic intraepithelial neoplasia (PIN) ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Prostatic intraepithelial neoplasia (PIN) represents the putative precancerous end of the morphologic continuum of cellular proliferations within prostatic ducts, ductules an acini. Two grades of PIN are identified (low grade and high grade), and high grade PIN is considered to be a precursor to invasive carcinoma. The continuum which culminates in high grade PIN and early invasive cancer is characterized by basal cell layer disruption, basement membrane disruption, progressive loss of secretory differentiation markers, increasing nuclear and nucleolar abnormalities, increasing proliferative potential, and increasing variation in DNA content (aneuploidy). Clinical studies suggest that PIN predates carcinoma by ten years or more, with low grade PIN first emerging in men in the third decade of life. The clinical importance of recognizing PIN is based on its strong association with carcinoma; its identification in biopsy specimens of the prostate warrants further search for concurrent invasive carcinoma. © 1992 Wiley-Liss, Inc.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 50 (1992), S. 31-38 
    ISSN: 0730-2312
    Keywords: bladder ; carcinoma in situ ; dysplasia ; invasion ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Non-invasive transitional cell carcinoma (TCC) occurs as two distinct growth patterns, papillary and non-papillary (flat), which display significant differences in biologic potential. Papillary carcinoma usually presents as a low-grade lesion which frequently recurs multiple times prior to invasion; conversely, non-papillary (flat) carcinoma in situ is usually high-grade at presentation (carcinoma in situ) and frequently associated with invasion. These lesions may occur together, although papillary cancer is more easily visualized cystoscopically due to its exophytic growth; flat carcinoma in situ is often vystoscopically invisible.This report reviews existing data concerning the prognostic value of pathologic grading and staging of non-invasive and early invasive TCC. Emphasis is placed on those studies reporting surgical treatment rather than other forms of treatment. © 1992 Wiley-Liss, Inc.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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