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  • 1
    Electronic Resource
    Electronic Resource
    Blood retinal and blood aqueous barriers in diabetics by fluorophotometry (1989)
    Springer
    Documenta ophthalmologica 71 (1989), S. 19-27 
    Details
    ISSN: 1573-2622
    Keywords: fluorophotometry ; blood retinal barrier ; permeability ; blood aqueous barrier ; diffusion coefficient ; diabetic retinopathy ; fluorescein angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The permeability of the blood retinal barrier (PBRB) and the diffusion coefficient into the anterior chamber (kd) in 20 insulin dependent (ID) and in 11 non-insulin dependent (NID) diabetics with various degrees of retinopathy were determined by fluorophotometry with a 25% accuracy. The difference of PBRB and the kd values between the NID and the ID patients was not significant (p 〉 0.05 and p 〉 0.22). The mean PBRB and the mean kd values differed significantly from those of a healthy population (p 〈 0.0013 and p = 0.025). A significant correlation was established between PBRB and diabetes duration (r = 0.55; p 〈 0.01) but not between PBRB or kd values and metabolic control (HbA1) (p 〉 0.5) or creatinine clearance (p 〉 0.5). The time integrals of unbound plasma fluorescein in the diabetics between the time of injection and 1 hour later were comparable with those of healthy controls. The difference between the mean PBRB value of diabetics with advanced retinopathy and that of a healthy population was significant (p 〈 0.003) but the difference for the mean values of diabetics with no or minimal background retinopathy was not (p 〉 0.2), indicating that PBRB values do not increase to an abnormal level while signs of diabetic retinopathy are absent on fluorescein angiography.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00155129
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Xenon arch photocoagulator used for transpupillary hyperthermia (1991)
    Springer
    Documenta ophthalmologica 78 (1991), S. 183-187 
    Details
    ISSN: 1573-2622
    Keywords: Hyperthermia ; near-infrared irradiation ; xenon arch photocoagulator ; experimental melanoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The technique of near-infrared irradiation to obtain tumour necrosis in experimental pigmented melanomas is described. The xenon arch photocoagulator was modified and adapted for hyperthermia treatment. The adaptations included: filtering the light and changing the electronics, the aiming beam and the diameter of the beam.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00165679
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The permeability of the corneal epithelium of Graves' ophthalmopathy as determined by fluorophotometry (1989)
    Springer
    Documenta ophthalmologica 73 (1989), S. 249-254 
    Details
    ISSN: 1573-2622
    Keywords: Graves ; ophthalmopathy ; corneal epithelium ; permeability ; fluorophotometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The function of the corneal epithelium was evaluated in 30 patients with Graves' ophthalmopathy in whom no signs of corneal disease were observed. This function was evaluated by determining the permeability values of the corneal epithelium for fluorescein using fluorophotometry. The permeability values of the patients were compared with those of 46 healthy individuals. A significant increase in the permeability values was seen in 11 (37%) patients and in two (4%) controls (p 〈 0.05). The difference in the mean permeability values between patients en controls was statistically significant (0.053 nm/sec. ± 0.043 SD and 0.038nm/sec. ± 0.017 SD, respectively, p 〈 0.05). No relation was found between the permeability alues of the corneal epithelium and the NOSPECS classification or the duration of the disease. There was a tendency for increased permeability values in patients having an exophthalmos larger than 20mm. (correl. coeff. = +0.3, p 〈 0.05).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00155094
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    Paper (German National Licenses)
    Fulltext
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