ISSN:
1573-2622
Keywords:
subacute sclerosing panencephalitis
;
ophthalmoscopy
;
fluorescein angiography
;
histopathology
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract This paper describes the fundus changes in 2 patients with subacute sclerosing panencephalitis (SSPE). In both cases the ocular involvement preceded the neurological symptoms by several months. In one patient a localized serous detachment in the macular region was associated with retinal infiltrates and in the second patient an atypical unilateral macular chorioretinitis was first diagnosed. The diagnosis of SSPE was suspected when neurological signs appeared and it was confirmed by the typical EEG changes and especially by the high titers of measles antibodies in serum and CSF. The affected left eye of the second patient could be studied histopathologically and presented mainly pigment epithelial changes at the level of the scar, edema of the external plexiform layer, retinal folds and a detachment and rupture of the internal limiting membrane.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00154703
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