ISSN:
1435-232X
Keywords:
TBP gene
;
gene mapping
;
(CAG)n repeat
;
FISH
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary TBP (TATA box-binding protein) participates in the expression of eukaryotic genes transcribed by RNA polymerases I, II, and III. Molecular cloning of human TBP revealed that the N-terminal region contains a polymorphic (CAG)n repeat. We report here the direct localization of human TBP gene to chromosome 6q2705→qter region by fluorescencein situ hybridization, using the cDNA clone with or without the (CAG)n repeat as a probe.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01892387
Permalink