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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of industrial microbiology and biotechnology 16 (1996), S. 163-170 
    ISSN: 1476-5535
    Keywords: Monascus ; pigments ; rubropunctatin ; monascorubrin ; rubropunctamine ; monascorubramine ; ankaflavin ; monascin ; mevinolin ; monacolin ; lovastatin ; ankalactone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract This review deals with polyketides produced by the filamentous fungusMonascus which include: 1) a group of yellow, orange and red pigments, 2) a group of antihypercholesterolemic agents including mevinolin and related compounds and 3) the newly discovered metabolite ankalactone. Biosynthesis, methods of production, isolation and biological activities of these secondary metabolites are discussed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-4927
    Keywords: methylglyoxal ; methylglyoxal dehydrogenase loci 1, 2, 3 ; Mgd1 polymorphism ; heart-specificMgd3 expression ; glyoxalase I ; rat chromosome 13
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract A genetic locus controlling the electrophoretic mobility of a methylglyoxal dehydrogenase (EC 1.2.1.23) in the rat is described. The locus, designatedMgd1, is expressed in liver and kidney. Inbred rat strains have fixed either alleleMgd1 a or alleleMgd1 b . Codominant expression is observed in heterozygotes, providing evidence for a tetrameric enzyme structure. Backcross progenies showed the expected 1:1 segregation ratio, and there is evidence thatMgd1 is linked toPep3 andFh1 on chromosome 13. There is also evidence for two additional methylglyoxal dehydrogenases:Mgd2, present in liver and kidney, andMgd3, present only in heart.
    Type of Medium: Electronic Resource
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