ISSN:
1573-5168
Keywords:
T3
;
estradiol-17β
;
ovary
;
trout
;
gonadotropin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The cellular mechanism of action of 3,5,3′-triiodo-L-thyronine (T3) in enhancing SG-G100 gonadotropin-induced ovarian secretion of 17β-estradiol (E2) was studiedin vitro using oocyte follicular preparations of rainbow trout. The dependence of the T3 stimulatory action on the level of intracellular 3′,5′-cyclic adenosine monophosphate (cAMP) was shown in experiments in which forskolin or dibutyryl cAMP enhanced E2 secretion. In the presence of partially purified salmon gonadotropin (SG-G100), T3 stimulation of E2 secretion was prevented by theophylline, suggesting that T3 may exert part of its stimulatory action by inhibiting phosphodiesterase.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01875028
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