ISSN:
1573-7217
Keywords:
breast cancer
;
EGF binding
;
growth rate
;
mitoses
;
nodal status
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Number of mitoses and EGF binding were determined in parallel in biopsies of 27 lymph-node positive and of 23 lymph-node negative breast cancer patients. For node-positive patients the parameters for cell growth and EGF binding were quantitatively correlated by the equation y = P3 + P1(1 − exp( − P2x)). For node-negative cases neither the non-linear model nor the linear approximation described the data unambiguously. The results strongly suggest that in node-positive patients, growth of breast cancer is related to an EGF-dependent acceleration of cell division.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01805739
Permalink
