ISSN:
1573-8221
Keywords:
hypochlorite
;
lipid peroxidation
;
cholesterol
;
phosphatidylcholine
;
liposomes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The effect of cholesterol on hypochlorite-induced lipid peroxidation is studied in cholesterol-phosphatidylcholine liposomes. Cholesterol is shown to promote the accumulation of lipid peroxidation products in the presence of 0.1–3 mM hypochlorite anion in the incubation medium. The content of 2-thiobarbituric acid-reactive products is maximal at a cholesterol: phosphatidylcholine molar ratio of 1∶1. On the other hand, in the presence of low hypochlorite concentrations (10–100 μM) cholesterol is found to inhibit lipid peroxidation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02446938
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