ISSN:
0942-0940
Keywords:
SAH
;
immunology
;
mitogenic response of lymphocytes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Proliferative response to mitogens concanavalin A, phytohaemoagglutinin and pokeweed mitogen, and other chosen indicators of the activity of the immune system were assayed in peripheral blood mononuclear cells isolated from blood of patients with subarachnoid haemorrhage from ruptured aneurysm. Healthy blood donors served as control group. The SAH group displayed impaired response to concanavalin A, which is a mitogen specific for suppressor cells. It is suggested that the impaired activity of suppressor cells pre-existed in patients with subarachnoid haemorrhage, and after intracranial bleeding it might have contributed to the development of late neurological deficits.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01405536
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