Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • obesity  (3)
  • infrared spectroscopy  (2)
  • rat chromosome 12  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Roles of deoxycholate and arachidonate in pathogenesis of cholesterol gallstones in obese patients during rapid loss of weight (1991)
    Springer
    Digestive diseases and sciences 36 (1991), S. 957-960 
    Details
    ISSN: 1573-2568
    Keywords: gallstone ; deoxycholate ; arachidonate ; obesity ; weight loss
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our aim was to examine the relationship between biliary deoxycholate and arachidonate in obese patients and the relationship of deoxycholate and arachidonate to the stimulation of biliary mucous glycoprotein among obese patients predisposed to cholesterol gallstones. Thirty-four obese patients predisposed to cholesterol gallstones by a weightreducing diet (520 kcal/day) received placebo, ursodiol (1200 mg/day), or aspirin (1300 mg/day). Duodenal bile was collected prior to beginning the diet and at four weeks. There was no correlation between deoxycholate and arachidonate among the 34 patients before beginning the diet. With placebo, deoxycholate decreased while arachidonate and glycoprotein increased. With ursodiol, deoxycholate decreased while arachidonate decreased and glycoprotein did not change. With aspirin, there was no change in deoxycholate but a decrease in arachidonate and no change in glycoprotein. Our data do not support a role for biliary deoxycholate in the regulation of biliary arachidonate. Our data do support a role for arachidonate, but not deoxycholate, in the regulation of biliary glycoprotein during the formation of cholesterol gallstones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297147
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Four polymorphic markers on rat chromosome 12 form a single linkage group (1993)
    Springer
    Biochemical genetics 31 (1993), S. 441-448 
    Details
    ISSN: 1573-4927
    Keywords: linkage analysis ; serine dehydratase ; plasminogen activator inhibitor ; simple sequence repeats ; microsatellites ; rat chromosome 12
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Four PCR-typable polymorphic markers were mapped to rat chromosome 12 by linkage analysis of F2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) rat strains. The markers formed a single linkage group, covering 27.7 cM, with the following order and distance between markers: plasminogen activator inhibitor (Planh)—0.0 cM—phosphoenolpyruvate carboxykinase-related sequence 2 (Pepckr2)—15.4 cM—anonymous marker (D12N155)—12.3 cM—serine dehydratase (Sdh). All markers were identified and genotyped by PCR analysis of simple sequence repeats. The gene encoding Planh was previously assigned to rat chromosome 12, which allowed us to assign the entire linkage group to this chromosome. These markers were highly polymorphic in 13 additional inbred rat strains (BUF/N, BN/SsN, WKY/N, MNR/N, LER/N, WBB1/N, WBB2/N, MR/N, LOU/MN, SHR/N, ACI/N, SR/Jr, and SS/Jr). These markers should be useful tools for further genetic studies in rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00553460
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Four polymorphic markers on rat chromosome 12 form a single linkage group (1993)
    Springer
    Biochemical genetics 31 (1993), S. 441-448 
    Details
    ISSN: 1573-4927
    Keywords: linkage analysis ; serine dehydratase ; plasminogen activator inhibitor ; simple sequence repeats ; microsatellites ; rat chromosome 12
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Four PCR-typable polymorphic markers were mapped to rat chromosome 12 by linkage analysis of F2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) rat strains. The markers formed a single linkage group, covering 27.7 cM, with the following order and distance between markers: plasminogen activator inhibitor (Planh)—0.0 cM—phosphoenolpyruvate carboxykinase-related sequence 2 (Pepckr2)—15.4 cM—anonymous marker (D12N155)—12.3 cM—serine dehydratase (Sdh). All markers were identified and genotyped by PCR analysis of simple sequence repeats. The gene encoding Planh was previously assigned to rat chromosome 12, which allowed us to assign the entire linkage group to this chromosome. These markers were highly polymorphic in 13 additional inbred rat strains (BUF/N, BN/SsN, WKY/N, MNR/N, LER/N, WBB1/N, WBB2/N, MR/N, LOU/MN, SHR/N, ACI/N, SR/Jr, and SS/Jr). These markers should be useful tools for further genetic studies in rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02396228
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Effects of ursodiol or ibuprofen on contraction of gallbladder and bile among obese patients during weight loss (1996)
    Springer
    Digestive diseases and sciences 41 (1996), S. 242-249 
    Details
    ISSN: 1573-2568
    Keywords: weight loss ; ursodiol ; ibuprofen ; gallbladder ; bile ; gallstones ; obesity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Rapid loss of weight in obese patients is associated with increased saturation of bile with cholesterol, increased nucleation and growth of cholesterol crystals, and gallstones. The aims of this study were to determine the effects of rapid weight loss on contraction of the gallbladder and to evaluate the effects of ursodiol and ibuprofen on saturation, nucleation and growth, and contraction. Forty-seven obese patients entering a very low calorie dietary program were randomized to receive ursodiol, 1200 mg/day, ibuprofen, 1600 mg/day, or placebo for 12 weeks. Contraction of the gallbladder to a liquid meal was evaluated by ultrasonography, and duodenal bile was collected initially and after six and 12 weeks. Diet caused reduced contraction of the gallbladder, increased cholesterol saturation, and increased nucleation and growth of crystals. Ursodiol reduced saturation and prevented increases in nucleation and growth and contraction. Ibuprofen prevented the increase in saturation and the reduction in contraction with a trend opposing the increase in nucleation and growth. In conclusion, during dieting, contractility of the gallbladder to meals is reduced. The effectiveness of ursodiol in preventing gallstones may be explained partially by effects on contraction. Ibuprofen deserves further study because of its effects on saturation, nucleation and growth, and contraction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02093811
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Risk factors for gallstone formation during rapid loss of weight (1992)
    Springer
    Digestive diseases and sciences 37 (1992), S. 912-918 
    Details
    ISSN: 1573-2568
    Keywords: gallstone ; gallstone formation ; weight loss ; obesity ; risk factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Risk factors for the development of gallstones during rapid weight loss were assessed in 457 subjects who entered a weight control program (520 kcal/day). Absence of gallstones in these subjects was documented by ultrasonography prior to entry into the study. Ultrasonography was performed again at 16 weeks on the subjects who remained in the study (N=248). The incidence of gallstones by 16 weeks of rapid weight loss was 10.9% (27/248). Most factors associated with gallstones in the general population, eg, older age, female gender, parity, positive family history, etc, were not associated with gallstones in this population. The risk factors for developing gallstones included increased initial body mass index [weight (kg)/height (m)2], amount of body mass index loss, and serum triglyceride levels. The positive predictive value of these risk factors was 75%, but the sensitivity was only 12%. These observations indicate that risk factors for the development of gallstones during rapid weight loss are probably different from those in the general population. The factors identified by this study are useful in predicting patients at high risk for gallstones. However, since only a minority of gallstones that form can be predicted, further study is needed to identify additional factors that will improve our ability to predict gallstone formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01300390
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Electric field-induced dipole reorientation in oriented nylon 11 by in situ infrared spectroscopy (1996)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 34 (1996), S. 781-788 
    Details
    ISSN: 0887-6266
    Keywords: nylon ; infrared spectroscopy ; electric field poling ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Dipole reorientation under the influence of an electric field is investigated in oriented nylon 11 films with polarized infrared spectroscopy for the amide A and amide I bands. Butterfly-shaped hysteresis loops are obtained from peak intensity versus applied electric field strength. Least-squares Gaussian curve fitting of the resolved multiple contributions to the amide I peak show that the components change in either a continuously reducing S-shaped fashion, or in butterfly-shaped curves under ac poling fields. Time-dependent studies of the absorption intensities show that both ordered and disordered species switch towards the electric field direction with the application of electric fields higher than the coercive field. Upon field removal, only the disordered species show orientation relaxation away from the field direction. Below the coercive field, neither species responds orientationally to the field. © 1996 John Wiley & Sons, Inc.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
  • 7
    Electronic Resource
    Electronic Resource
    Fermi resonance in the infrared spectra of Nylon-11 (1992)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 30 (1992), S. 1073-1080 
    Details
    ISSN: 0887-6266
    Keywords: Nylon-11 ; infrared spectroscopy ; Fermi resonance ; crystal structures ; symmetry ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Nylon-11 is prepared by casting from the solvents trifluoroacetic acid and m-cresol and by melt-crystallization. Room-temperature infrared spectra are compared in terms of possible crystal structures. The spectra are examined for the presence of Fermi resonance which occurs between the N-H stretching fundamental mode and the overtone and combination modes of the amide I and II vibrations. An analysis of peak frequencies and intensities is used to provide support for the assignment of the amide II overtone and the amide I + II combination modes. A newly observed peak in the spectra is assigned to the amide I overtone. Symmetry considerations are discussed which predict the resonance of the overtone and combination modes with the N-H stretching fundamental. © 1992 John Wiley & Sons, Inc.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/polb.1992.090301001
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...