ISSN:
1432-2277
Keywords:
Key words Liver transplantation
;
factor VII deficiency
;
Factor VII deficiency
;
liver transplantation
;
Liver transplantation
;
disease transmission
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The liver is the primary site of synthesis for the majority of coagulation factors. There are published accounts of liver donor-to-recipient transmission of protein C deficiency with dysfibrinogenemia and factor XI deficiency. In this article, we report what we believe to be the first observation, of transmission of factor VII deficiency, a rare, autosomal recessive coagulation disorder, from an affected liver donor to a naive liver recipient. At 300 days after transplantation, the recipient remains with an isolated prolongation of the prothrombin time and a below-normal level of factor VII, and has had no bleeding complications.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s001470050223
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