ISSN:
1573-8221
Keywords:
cell culture
;
mitotic regime
;
pathological mitoses
;
suboptimal temperature
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Keeping Chinese hamster cells for 2 h at a suboptimal temperature (21°C) leads to a fall in the mitotic index and delay of division at the metaphase state. Cooling cause a sharp increase in the number of pathological mitoses, mainly as a result of injury to the mitotic apparatus: C mitoses and dispersion of the chromosomes in metaphase. After transfer of the cells to optimal temperature conditions the mitotic regime is completely restored after 1 h, but at this time the number of pathological mitoses is still appreciably greater than in the control.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00799432
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