ISSN:
1573-6776
Keywords:
α-chymotrypsin
;
Mucor javanicus
;
optical resolution
;
2-(3-indolyl)propionic acid
Source:
Springer Online Journal Archives 1860-2000
Topics:
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Abstract Resolution of 2-(3-indolyl)propionic acid was achieved via biocatalytic hydrolysis of its chloroethyl ester. Of the enzymes tested, Mucor javanicus lipase (R selectivity) and α-chymotrypsin (S selectivity) had high reactivity and enantioselectivity (E value 〉 50). Neither enzyme showed enantioselectivity (E value = 1) for 2-phenylpropionic acid.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1005550806687
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