ISSN:
1435-1536
Keywords:
Poly-L-Lys
;
branched polypeptides
;
poly-L-Lys-poly-DL-Ala
;
GPC of synthetic polypeptides
;
sedimentation analysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract Three different poly-L-lysine (pLys) samples and a branched polypeptide poly-[L-Lys-(DL-Ala)m] (poly-L-Lys-poly-DL-Ala, AK) were synthetized. Relative molar mass distribution, its average and the degree of polymerisation were determined by sedimentation analysis and gel permeation chromatography (GPC). The conformation of the polymers in solution was studied by circular dichroism (CD) spectroscopy at various pH values and ionic strengths. The data obtained by different methods were compared.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01458962
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