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Digitale Medien

Role of reactive oxygen species (ROS) in apoptosis induction (2000)

Simon, H.-U. ; Haj-Yehia, A. ; Levi-Schaffer, F.

Springer

Apoptosis 5 (2000), S. 415-418

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Details

ISSN: 1573-675X

Schlagwort(e): apoptosis ; death receptors ; inflammation ; reactive oxygen species (ROS)

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Abstract Reactive oxygen species (ROS) and mitochondria play an important role in apoptosis induction under both physiologic and pathologic conditions. Interestingly, mitochondria are both source and target of ROS. Cytochrome c release from mitochondria, that triggers caspase activation, appears to be largely mediated by direct or indirect ROS action. On the other hand, ROS have also anti-apoptotic effects. This review focuses on the role of ROS in the regulation of apoptosis, especially in inflammatory cells.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1023/A:1009616228304

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