ISSN:
1573-8221
Keywords:
sodium hydroxybutyrate
;
physical exertion
;
ultrastructure of the myocardium and skeletal muscles
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The ultrastructure of myocytes in the rat myocardium and skeletal muscles was studied during physical exertion in a control group and after preliminary administration of sodium hydroxybutyrate for 2 weeks. A single exposure to maximal physical exertion was shown to cause considerable changes in the fine structure of the cardiomyocytes and, to a rather lesser degree, in the myocytes of skeletal muscles. These changes consisted of masked intermyofibrillary edema, swelling of the mitochondria, and a sharp decrease in the glycogen level. Sodium hydroxybutyrate, if given for 2 weeks beforehand, prevents the changes described above in the myocytes. Normalization of structure observed under the influence of the compound can evidently be attributed to the character of its metabolic conversion and its effect on energy metabolism.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00799289
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