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Tizanidine in the treatment of spasticity (1982)

Newman, P. M. ; Nogues, M. ; Newman, P. K. ; [et al.]

Springer

European journal of clinical pharmacology 23 (1982), S. 31-35

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ISSN: 1432-1041

Keywords: tizanidine ; baclofen ; spasticity ; double-blind crossover studies ; open trial

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary A double-blind crossover trial compared tizanidine with baclofen in 36 patients with spasticity. Tizanidine appeared to reduce lower limb spasticity more effectively and to have fewer side effects, but no statistically significant differences emerged when the two drugs were compared. An additional open study of tizanidine confirmed the beneficial action in a selected minority of patients with spasticity. This drug may have an important role in the management of spasticity, but further studies are required.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01061374

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