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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 9 (1988), S. 351-354 
    ISSN: 1590-3478
    Keywords: Blink reflex ; dopamine ; substantia nigra ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Su 12 volontari adulti, neurologicamente indenni, sono stati studiati gli effetti indotti dalla somministrazione di un farmaco dopaminolitico (aloperidolo, 6 mg/die × 2 giorni) sul riflesso di ammiccamento (blink reflex). Si è osservato un significativo aumento dell'ampiezza della componente precoce (R1) del riflesso, con un ritorno alla norma entro 5 giorni dalla cessazione della somministrazione del farmaco. Vengono discussi i possibili circuiti nervosi coinvolti negli effetti osservati.
    Notes: Abstract The effect of the anti-dopaminergic drug haloperidol (6 mg/day i.m. for 2 days) on the blink reflex elicited by electric stimulation of supraorbital nerves was investigated in 12 adult volunteers. A significant increase in amplitude of the early component (R1) of the reflex was observed. This increase disappeared within 5 days of stopping the drug. Possible neural systems which might be involved in these effects are considered.
    Type of Medium: Electronic Resource
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