ISSN:
1573-4943
Keywords:
Calcium-binding lysozyme
;
α-lactalbumin
;
three-dimensional structure
;
evolution
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Similarities in amino acid sequences, three-dimensional structures, and the exon-intron patterns of their genes have indicated thatc-type lysozymes andα-lactalbumins are homologous proteins, i.e., descended by divergent evolution from a common ancestor. Like theα-lactalbumins, echidna milk, horse milk, and pigeon eggwhite lysozymes all bind Ca(II). Models of their three-dimensional structures, based on their amino acid sequences and the known crystal structures of domestic hen eggwhite and human lysozymes and baboon and humanα-lactalbumins, have been built. The several structures have been compared and their relationships discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01901539
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