ISSN:
1573-4919
Keywords:
Rdy cat
;
photoreceptor degeneration
;
two-dimensional gel electrophoresis
;
polypeptides
;
rod outer segments
;
visual transduction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
Notes:
Abstract A preparation of rod outer segments has been used to study the polypeptides characteristic of an early-onset retinal dystrophy in cats (Rdy) by two-dimensional gel electrophoresis. Comparison of 2-D gels of rod outer segment preparations from retinas of normal and Rdy animals shows several differences. In particular, a polypeptide of Mr 51 kDa and pI 7.5 is present at increased levels in preparations from Rdy cats at 6 weeks, 9 weeks and 12.5 weeks of age but not at 3.5 weeks.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00225514
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