ISSN:
1573-7373
Keywords:
central nervous system
;
lymphoma
;
T-cell
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Primary central nervous system (CNS) involvement of non-Hodgkin's lymphoma is uncommon and a vast majority of reported cases are of B-cell origin. We present a 52-year-old woman with primary peripheral T-cell lymphoma of the brain. Immunostaining of paraffin-embedded sections proved tumor cells to be positive for T-cell markers MT1 and UCHL1, and negative for B-cell markers MB1, and 4KB5. Radiotherapy combined with steroid therapy rendered neurologic recovery and complete tumor remission confirmed by computed tomography and magnetic resonance imaging. From a review of documented 19 cases of primary CNS T-cell lymphoma including the present case, this disease is characterized by poor prognosis among CNS lymphomas.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01057040
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