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  • 1
    Electronic Resource
    Electronic Resource
    Is actin in eye lens a possible factor in visual accommodation? (1980)
    [s.l.] : Nature Publishing Group
    Nature 285 (1980), S. 506-508 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sections, 4 µm thick, were obtained by cutting calf lenses in three mutually perpendicular directions, and incubated with specific antisera. A rabbit antiserum was raised against purified actin isolated from calf lens3. Antibodies against actin are also known to be present in the serum of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/285506a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Endophthalmitis: Incidence, therapy and visual outcome in the period 1983–1992 in the Rotterdam Eye Hospital (1992)
    Springer
    Documenta ophthalmologica 82 (1992), S. 115-123 
    Details
    ISSN: 1573-2622
    Keywords: Antibiotic therapy ; Endophthalmitis ; Ocular surgery ; Ocular trauma ; Vitrectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract From 1983 to 1992, 134 patients were treated for clinically suspected endophthalmitis. 61% of this endophthalmitis population consisted of cases that were referred to our clinic. In this nine year period antibiotic treatment was carried out according to three consecutively used guidelines. These three treatment schemes differed in antibiotic spectrum and mode of antibiotic delivery. In 68 patients we performed vitrectomy on account of clinical deterioration under antibiotic treatment. We did not find significant differences in visual outcome between the three treatment groups. The incidence of endophthalmitis following cataract or vitreous surgery did not change throughout the study period. There was however a dramatic decrease in incidence of post-traumatic endophthalmitis following the introduction of a profylactic antibiotic treatment scheme consisting of fortified gentamicin and cefazolin eyedrops, and intravenously and subconjunctivally administered gentamicin, cefazolin, and clindamycin. In 55 of 68 cases in which vitrectomy was performed in conjunction with intravitreal antibiotics, a vitreous or anterior chamber specimen was cultured. 36 patients had a positive culture result. In the group with positive culture result 42% had better visual acuity in the post-treatment period than before treatment. In the group with a sterile culture result 79% had better vision after treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00157001
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  • 3
    Electronic Resource
    Electronic Resource
    Monoclonal antibodies in detection of choroidal melanoma (1989)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 227 (1989), S. 287-290 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Three monoclonal antibodies (MoAbs) prepared against cutaneous melanomas were tested against one group of 12 choroidal melanomas with indirect immunofluorescence in frozen sections. A fourth MoAb was tested in paraffin sections of a second group of 47 choroidal melanomas. One MoAb (NKI-M7) did not react with choroidal melanoma, even though it had a high sensitivity for cutaneous melanoma. A second MoAb (NKI-M6) showed a positive reaction with only 2/12 choroidal melanomas. The third MoAb (NKI/beteb) reacted with all choroidal melanomas, regardless of the cell type. MoAb NKI/C-3 was positive with 38/47 (81%) choroidal melanomas. We conclude that NKI/C-3 and NKI/beteb have a high sensitivity for both cutaneous and choroidal melanomas in frozen sections. Of these two antibodies NKI/beteb was the most specific for cutaneous naevi and melanomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02172764
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