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Digitale Medien

The significance of the subcompartments of the marginal zone for directing lymphocyte traffic within the splenic pulp of the rat (1982)

Brelińska, Renata ; Pilgrim, Christoph

Springer

Cell & tissue research 226 (1982), S. 155-165

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Details

ISSN: 1432-0878

Schlagwort(e): Spleen (rat) ; Lymphocytes ; Autoradiography

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary These studies were designed to gain more detailed information on the sites of lymphocyte migration into the marginal zone, on lymphocyte segregation within this area and on subsequent migration of the cells in individual compartments of the rat spleen. A lymphocyte population enriched in T-lymphocytes was obtained from rat lymph nodes and was labeled with 5-(3H)uridine in vitro. Observations on localization of labeled lymphocytes at short time intervals following their intravenous transfusion into syngeneic recipients, indicate that the sites of emigration from the blood are the internal and external layers of the marginal zone. From here, the cells migrate towards the periarteriolar lymphoid sheath and the red pulp.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00217090

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