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  • 11
    Electronic Resource
    Electronic Resource
    Messung der aktuellen Pulpadurchblutung nach orthodontischer Kraftapplikation (1996)
    Springer
    Journal of orofacial orthopedics 57 (1996), S. 306-309 
    Details
    ISSN: 1615-6714
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The purpose of the present investigation was to measure the effect of tooth intrusion and extrusion on pulpal blood flow in man. The flow changes were measured in 10 lateral incisors (6 subjects) by means of laser Doppler flowmetry (Perimed, Sweden) applied on the buccal surface through metal tubes bonded to the teeth. Brackets were bonded onto teeth 13 and 23, and intrusive and extrusive forces of 2 N were applied in random order to the experimental tooth for 5 min before unloading. The contralateral tooth served as a control. Extrusion of the teeth gave no significant changes in pulpal blood flow during loading or unloading, However, intrusion of the teeth reduced the pulpal blood flow by 20% during the first minute after force application. The pulpal blood flow gradually increased towards the preloading flow values for the next 4 min, and was returned to the prestimulus level 3 min after unloading. In conclusion orthodontic intrusion of teeth with a 2 N force evoked a temporary reduction in the pulpal blood flow, whereas extrusion had no effect on the pulpal blood flow.
    Notes: Zusammenfassung Das Ziel der hier vorgestellten Untersuchung war es, die Auswirkung von Intrusion sowie Extrusion auf die Blutversorgung der Pulpa am Menschen zu ermitteln. Die Unterschiede der Durchblutungsänderungen wurden an zehn lateralen Inzisiven (sechs Probanden) durch Laser Doppler Flowmetry (Perimed, Sweden) mittels an den bukkalen Flächen der Zähne befestigter Metallröhrchen gemessen. Die Brackets wurden an den Zähnen 13 und 23 befestigt, und intrusive bzw. extrusive Kräfte von 2 N wurden an den zu untersuchenden Zähnen über einen Zeitraum von fünf Minuten appliziert. Der jeweilige kontralaterale Zahn diente als Kontrolle. Die Extrusion bewirkte keine signifikante Veränderung des Pulpablutdurchflusses weder während noch nach der Aufhebung der extrusiven Kräfte. Intrusive Kräfte reduzierten jedoch während der ersten Minute der Kraftapplikation den Pulpablutdurchfluß um 20%. Während der nächsten vier Minuten kam es zu einer kontinuierlichen Zunahme des Pulpablutdurchflusses in Richtung des Ausgangswertes, und drei Minuten nach Aufhebung der Kraft erreichte er wieder den normalen Wert. Zusammenfassend kann festgestellt werden, daß die orthodontische Intrusion mit einer Kraft von 2 N eine temporäre Reaktion des Pulpablutdurchflusses hervorrief, die Extrusion hingegen keine Auswirkung auf den Pulpablutdurchfluß hatte.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02197551
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  • 12
    Electronic Resource
    Electronic Resource
    Enhanced Sensory Reinnervation of Dental Target Tissues in Rats Following Low Level Laser (LLL) Irradiation (1999)
    Springer
    Lasers in medical science 14 (1999), S. 177-184 
    Details
    ISSN: 1435-604X
    Keywords: Keywords: Calcitonin gene related peptide; Dental pulp; Immunohistochemistry; Inferior alveolar nerve axotomy; Low level laser; Nerve regeneration; Photobiostimulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract . Previous studies have suggested that low level laser (LLL) treatment at specific wavelengths can enhance motor and sensory function in peripheral nerves after injury. The dental pulp is innervated by unmyelinated C fibres and small myelinated Aδ fibres derived from the trigeminal ganglion, both of which are known to contain calcitonin gene related peptide (CGRP). The aim of the present study was to examine the effects of daily LLL treatment on the sensory reinnervation of the first molar pulp 10 days subsequent to inferior alveolar nerve (IAN) axotomy, by counting the number of nerve fibre profiles immunoreactive to CGRP in rats. Axotomy of the IAN was performed via an extraoral buccal incision. The animals (n=11) were divided into two groups receiving either daily LLL treatment with a GaAlAs laser (λ=830 nm), or sham laser treatment over the site of injury for 10 days postoperatively. The animals were transcardially perfused and fixed at death before excising the jaws for further fixation and demineralisation. The jaws were cryosectioned obliquely through the mesial root pulp of the first molar tooth, which was the chosen level for evaluation of reinnervation. The CGRP antigen–antibody binding sites were visualised using a standard avidin biotin peroxidase technique. Both sham and LLL treatment and the evaluation of results were conducted blind. The results were statistically analysed and presented as median with 25%–75% quartiles. A statistically significant (p≤0.0000) greater number of CGRP immunoreactive nerve profiles were seen in the LLL-treated group (median=5, range 4–6) compared to the sham laser treated group (median=2, range 1–3), at the specified area for evaluation. These results suggest that LLL treatment can enhance reinnervation of denervated dental tissues after IAN axotomy in the rat. The enhanced reinnervation could be due to accelerated regeneration of the axotomised nerve, to collateral reinnervation, or a combination of both these nerve responses. The mechanisms whereby these changes are effected are still unknown.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101030050082
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    Paper (German National Licenses)
    Fulltext
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