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  • 11
    Electronic Resource
    Electronic Resource
    Molecular action of tricholin, a ribosome-inactivating protein isolated from Trichoderma viride (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 5 (1991), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: An extracellular protein was isolated from a species of soil-borne fungi (Trichoderma viride) and its amino acid composition has been determined. The protein is acidic with a molecular mass of 14 200 daltons and is given the trivial name tricholin. Tricholin is a potent inhibitor of cell-free protein synthesis. When rabbit reticulocyte lysate was incubated with tricholin at a concentration of 6.3 × 10−7 M, it completely abolished the capacity of the lysate to support protein synthesis. The inhibition appears to be due to its reaction to ribosomes, since it generates a specific cleavage product, an α-sarcin RNA fragment, from reticulocyte ribosomal RNA. This reaction to ribosomes mimics that of α-sarcin. The antibody of α-sarcin strongly cross-reacts with tricholin, while the antibody of tricholin shows a weak reaction with α-sarcin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1991.tb01860.x
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  • 12
    Electronic Resource
    Electronic Resource
    DNA homologies shared among E. corrodens isolates and other corroding bacilli from the oral cavity (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 25 (1990), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In a previous microbiological study of Eikenella corrodens, we noted the presence of E. corrodens strains with variability in colony morphology, as well as other corroding bacilli phenotypically similar to E. corrodens but which were unidentifiable on the basis of biochemical reactions. This raised questions as to whether E. corrodens constitutes a genetically heterogeneous group of organisms, and whether the unidentified corroding bacilli represent atypical E. corrodens or genetically unrelated organisms. In the present study, the genetic relationship among 14 E. corrodens isolates and 6 unidentified corroding bacilli was examined. DNA base compositions were determined from the melting temperatures of DNA samples. DNA homologies among E. corrodens and corroding bacilli were determined by DNA hybridization in solution using S1 nuclease. The % G + C content of E. corrodens strains varied from 56 to 58%, and from 56 to 60% for unidentified corroding bacilli. The DNA homologies among 12 E. corrodens isolates and 2 reference strains varied from 57 to 97%. Although these E. corrodens isolates exhibited variabilities in colony morphology and biochemical profile, no subspecies was identified. The unidentified corroding bacilli shared less than 33% homology with either of the E. corrodens reference strains. These corroding bacilli were further divided into 3 species on the basis of DNA hybridization studies using radiolabeled DNA from 2 representative corroding bacilli. One of the unidentified corroding bacilli appears to be a component of the normal flora in the human oral cavity. Our results indicate that E. corrodens is a genetically homogeneous species containing no recognizable subspecies. However, the oral microflora of periodontally healthy and diseased subjects contains other corroding bacilli which are recovered on media considered selective for E. corrodens. These organisms are morphologically and biochemically similar to E. corrodens but are genetically distinct. Such organisms are found frequently in the human oral cavity and may be easily confused with E. corrodens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1990.tb00900.x
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  • 13
    Electronic Resource
    Electronic Resource
    Near-tip microcrack shielding in advanced ceramics (2004)
    PO Box 1354, 9600 Garsington Road, Oxford OX4 2XG, UK. : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 27 (2004), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Recent manufacturing of advanced ceramics has developed phase transformation and cracks tilted or bridged to enhance ceramic-inherent toughness. However, main crack and near-tip microcracks interaction is another prominent means in toughening of the ceramic materials. In this study, mechanics of discrete model combined with alternative iterating numerical technique is developed and applied in assessment of main–microcrack interaction. Consequences of main–microcrack interaction can either shield or amplify the resulting main crack stress intensity factor, which accounts for the increase or decrease of ceramic toughness. Numerical outcomes show good agreement with the available solutions in the literatures; in addition results also reveal that the toughness shielding or amplification is dependent on the type of loadings as well as location/orientation of the microcrack. Nevertheless, residual normal stress plays an important role in shielding/amplification region trade-off. This work may provide a useful quantitative tool in ceramic design and a valuable insight into main–micro interaction phenomenon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.2004.00718.x
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  • 14
    Electronic Resource
    Electronic Resource
    Alternating iteration method for interacting multiple crack problems (1999)
    Oxford, UK : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 22 (1999), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-2695.1999.00214.x
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  • 15
    Electronic Resource
    Electronic Resource
    Io: A source for Jupiter's inner plasmasphere
    Amsterdam : Elsevier
    Icarus 31 (1977), S. 1-10 
    Details
    ISSN: 0019-1035
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0019-1035(77)90067-7
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  • 16
    Electronic Resource
    Electronic Resource
    Reactions of difluorosilylene with cyclopentene and cyclohexa-1,3-diene
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 226 (1982), S. 21-34 
    Details
    ISSN: 0022-328X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0022-328X(00)83388-4
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  • 17
    Electronic Resource
    Electronic Resource
    Energy dependence of heavy ion collisions ^4He + ^1^2C and ^1^2C + ^1^2C elastic scattering
    Amsterdam : Elsevier
    Nuclear Physics, Section A 477 (1988), S. 713-722 
    Details
    ISSN: 0375-9474
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9474(88)90414-9
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  • 18
    Electronic Resource
    Electronic Resource
    Regulators of G-protein signalling: a novel protein family involved in timely deactivation and desensitization of signalling via heterotrimeric G proteins (1999)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 360 (1999), S. 14-26 
    Details
    ISSN: 1432-1912
    Keywords: Key words Heterotrimeric G proteins ; GTPase-activating proteins ; RGS proteins ; Recovery ; Desensitization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a variety of signalling pathways heterotrimeric guanine-nucleotide-binding proteins (G proteins) trigger physiological responses elicited by hormones, neurotransmitters and sensory stimuli. Receptor-induced GDP/ GTP exchange activates G proteins by dissociating G-protein α-subunits from the βγ-dimers. Both α-subunits and βγ-dimers are involved in effector regulation. The deactivation of these active forms is controlled by the hydrolysis of GTP bound to α-subunits, allowing the inactive heterotrimer to reform. Termination of G-protein-mediated signalling in vivo is 10- to 100-fold faster than the in vitro rate of GTP hydrolysis by α-subunits, suggesting that in analogy to the GTPases of the Ras-superfamily, GTPase-activating proteins (GAPs) are required to achieve timely deactivation. Recently, members of a novel protein superfamily, known as “regulators of G-protein signalling” (RGS), were identified as potent GAPs for at least one subset of heterotrimeric G-protein α-subunits. In this review, we intend to discuss the proposed mechanism by which RGS proteins exert GAP activity for G-protein α-subunits as well as their specificities. The role of RGS proteins in desensitization and temporal resolution in certain signalling pathways will also be addressed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002109900031
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  • 19
    Electronic Resource
    Electronic Resource
    Surface spectroscopy (1982)
    Springer
    Applied physics 28 (1982), S. 229-232 
    Details
    ISSN: 1432-0649
    Keywords: 82.65 ; 68 ; 36.40 ; 78 ; 42.55
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00697849
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  • 20
    Electronic Resource
    Electronic Resource
    Developments in Phase-Field Modeling of Thermoelastic and Two-Component Materials (1999)
    Springer
    Journal of statistical physics 95 (1999), S. 1141-1164 
    Details
    ISSN: 1572-9613
    Keywords: solidification of alloys ; phase field models ; interfaces ; nonlocal effects ; solidus curves ; solute trappings ; partition coefficient ; asymptotics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A discussion is given of recent advances in phase-field modeling of materials which change phase. On one hand, general models incorporating elasticity properties of the material, nonconserved and conserved order parameters, and nonlocal effects are now available. On the other hand, gradient theories for binary alloys have been developed which reflect such effects as the dependence of capillarity on the concentration of impurities, solute trapping in its dependence on velocity of solidification fronts, and other nonequilibrium phenomena.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004566820463
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