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  • 11
    Electronic Resource
    Electronic Resource
    Maximum production in a bakers' yeast fed-batch culture by a tubing method (1981)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 23 (1981), S. 2069-2081 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A feedback control system of the glucose feed rate in a bakers' yeast fed-batch culture was developed by keeping the ethanol concentration constant. A PID controller and on-off controller were applied and discussed with the aid of the porous Teflon tubing method. Experimental results showed the effectiveness of the control system for avoiding the glucose effect and glucose starvation. It was shown that the feedback control system developed hare could achieve a maximum specific growth rate of 0.3 h-1 or a maximum cell yield of 0.5 g cell/g glucose in the fedhyphen;batch culture.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260230911
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    Paper (German National Licenses)
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  • 12
    Electronic Resource
    Electronic Resource
    Profile control scheme in a Bakers' yeast fed-batch culture (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 27 (1985), S. 1675-1686 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article develops and discusses a practical and useful computer control scheme so that the biomass concentration or the specific growth rate will as accurately as possible follow a desired profile specified in advance. Many computer simulations certified the validity of the proposed control scheme. The control scheme proposed, called “programmed-controller/feedback-compensator (PF) system,” consists of a programmed controller that will follow the desired profile unless there is noise or disturbance and a feedback compensator that will compensate the noise and correct error in the model parameters. As the feedback compensator, the model reference adaptive control (MRAC) algorithm was also proposed. The PF system with MRAC, named PF-MRAC, could be used sufficiently for the profile control of the specific growth rate. For the profile control of the cell concentration, “predictive control algorithm” should be added to the PF system, and the consequent control scheme was named as the PFP system. Many numerical examples showed that the PFP system with MRAC, named PFP-MRAC, proposed here worked sufficiently well.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260271208
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    Paper (German National Licenses)
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  • 13
    Electronic Resource
    Electronic Resource
    Start-up of chemostat: Application of fed-batch culture (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 21 (1979), S. 111-129 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A time-optimal strategy for start-up of a chemostat has been established by applying Miele's extremization method based on Green's theorem. The start-up time is always minimized by traveling along the uppermost boundary of the set of admissible domains on the (vx, μ) phase plane. The solutions are batch culture for monotone increasing growth kinetics and exponentially fed-batch culture followed by batch culture for substrate-inhibition kinetics. A time-suboptimal start-up strategy, exponentially fed-batch culture operated the same μ as that of chemostate, is proposed as more feasible than and physiologically preferable to the time-optimal strategies. The complete set of equations of operations necessary for performing each of the optimal and suboptimal start-ups is formulated. Numerical comparisons on the basis of continuous operation giving maximum productivities of cell-mass outputs show that differences in times required for start-up between optimal and suboptimal strategies are small.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260210109
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  • 14
    Electronic Resource
    Electronic Resource
    Optimal quality control of bakers' yeast fed-batch culture using population dynamics (1982)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 24 (1982), S. 2661-2674 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An optimal quality control policy for the overall specific growth rate of bakers' yeast, which maximizes the fermentative activity in the making of bread, was obtained by direct searching based on the mathematical model proposed previously. The mathematical model had described the age distribution of bakers' yeast which had an essential relationship to the ability of fermentation in the making of bread. The mathematical model is a simple aging model with two periods: Nonbudding and budding. Based on the result obtained by direct searching, the quality control of bakers' yeast fed-batch culture was performed and confirmed to be experimentally valid.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260241205
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    Paper (German National Licenses)
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  • 15
    Electronic Resource
    Electronic Resource
    Dynamics and control of an activated sludge process as a mixed culture system (1984)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 30 (1984), S. 368-376 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: One of the difficulties encountered in the operation of an activated sludge process is the phenomenon of bulking sludge.In an activated sludge process which is composed of a completely mixed aeration tank and a sedimentation vessel, the dynamic behavior of the system can be analyzed using a mathematical model. The model developed here is based on the kinetics and settleability of the combination of floc-forming sludge and bulking sludge. The operating conditions that cause the bulking phenomenon are clarified on the phase plane. It is also shown that a type of nonlinear state feedback regulator makes the system stable.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690300304
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    Paper (German National Licenses)
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