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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    The international journal of cardiovascular imaging 15 (1999), S. 35-39 
    ISSN: 1573-0743
    Keywords: fatty acids ; single photon emission computed tomography (SPECT) ; unstable angina
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Radionuclide imaging with BMIPP for assessment of myocardial metabolism can assist in clinical decision making in certain subsets of patients with coronary artery disease. In stable angina, abnormal BMIPP imaging and less BMIPP uptake than Tl-201 are more likely to be seen in the distribution of vessels with severe stenoses and related to regional wall abnormalities. BMIPP SPECT imaging is a promising approach in the evaluation of patients with suspected unstable angina during the pain-free period even after stabilization. Fatty acid metabolism is easily suppressed due to the abrupt onset of ischaemia. In addition, combined imaging with BMIPP and Tl-201 can provide insights into the understanding of abnormal metabolism in myocardium in stable and unstable angina. This review addressed the clinical applications of BMIPP imaging for evaluation of stable and unstable angina.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1615-2573
    Keywords: Immune tolerance ; Thymus gland-immunology ; Heart transplantation ; Heart ; myocardium ; transplantation ; Graft survival ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to induce immunological tolerance, intrathymic inoculation of incompatible donor myocardial cells in rats was performed in the neonatal period. Isolated myocardial cells harvested from donor rat hearts were inoculated into the thymus of incompatible neonatal recipient rats without administration of immunosuppressive agents. Ten weeks later, the hearts from the donors were transplanted heterotopically to these pretreated rats. The animals were sacrificed on the 7th day of heterotopic transplantation and were examined histopathologically. The results showed no early rejection in the group in which intrathymic myocardial cell inoculation had been performed in the neonatal period. Immunohistochemical staining for myoglobin of the thymus from the inoculated recipient revealed that the donor myocardial cells continued to survive. The longest proven graft survival in this series, thus far, was 60 days, while it was only 7 days in the control group.
    Type of Medium: Electronic Resource
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