ISSN:
1573-8221
Keywords:
pathology of mitosis
;
stathmokinetic effect
;
radiomimetic effect
;
chromosome bridges
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Experiments on fibroblast-like Chinese hamster cells showed that agents inducing c-mitosis (colchicine, colcemid, low temperature) give rise to two distinct effects: stathmokinetic and radiomimetic. Toward the time of reversibility of the first of these effects, the second becomes clearly manifested as bridge formation. The appearance of this pathological form is evidently due to disturbance of cell nucleoprotein metabolism during c-mitosis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00801403
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