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  • 1
    Digitale Medien
    Digitale Medien
    Electron-transfer kinetics of 4,4'-bis(alkoxycarbonyl)-2,2'-bipyridine-iron complexes in micellar solution (1985)
    s.l. : American Chemical Society
    Inorganic chemistry 24 (1985), S. 4533-4537 
    Details
    ISSN: 1520-510X
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/ic00220a023
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  • 2
    Digitale Medien
    Digitale Medien
    Proton spin relaxation study in solutions of beryllium nitrate in water and mixtures of water and dimethyl-d6 sulfoxide (1980)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 84 (1980), S. 1393-1400 
    Details
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/j100448a021
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  • 3
    Digitale Medien
    Digitale Medien
    Electron transfer in micellar systems. Separation of electrostatic and environmental effects for some electron-transfer reactions in micellar solutions of sodium dodecyl sulfate (1982)
    s.l. : American Chemical Society
    Inorganic chemistry 21 (1982), S. 2432-2436 
    Details
    ISSN: 1520-510X
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/ic00136a061
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  • 4
    Digitale Medien
    Digitale Medien
    Somatotopy in the Human Motor Cortex Hand Area. A High-Resolution Functional MRI Study (1997)
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 9 (1997), S. 0 
    Details
    ISSN: 1460-9568
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Fine-scale somatotopic encoding in brain areas devoted to sensorimotor processing has recently been questioned by functional neuroimaging studies which suggested its absence within the hand area of the human primary motor cortex. We re-examined this issue by addressing somatotopy both in terms of functional segregation and of cortical response preference using oxygenation-sensitive magnetic resonance imaging at high spatial resolution. In a first step, spatial representations of self-paced isolated finger movements were mapped by using motor rest as a control state. A subsequent experimental design studied the predominance of individual finger movements by using contrasting finger movements as the control task. While the first approach confirmed previous reports of extensive overlap in spatial representations, the second approach revealed foci of differential activation which displayed an orderly mediolateral progression in accordance with the classical cortical motor homunculus. We conclude that somatotopy within the hand area of the primary motor cortex does not present as qualitative functional segregation but as quantitative predominance of certain movement or digit representation embedded in an overall joint hand area.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1460-9568.1997.tb01384.x
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  • 5
    Digitale Medien
    Digitale Medien
    Functional MRI of the immediate impact of transcranial magnetic stimulation on cortical and subcortical motor circuits (2004)
    Oxford, UK : Blackwell Science, Ltd
    European journal of neuroscience 19 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Recent studies indicate that the cortical effects of transcranial magnetic stimulation (TMS) may not be localized to the site of stimulation, but spread to other distant areas. Using echo-planar imaging with blood-oxygenation-level-dependent (BOLD) contrast at 3 Tesla, we measured MRI signal changes in cortical and subcortical motor regions during high-frequency (3.125 Hz) repetitive TMS (rTMS) of the left sensorimotor cortex (M1/S1) at intensities above and below the active motor threshold in healthy humans. The supra- and subthreshold nature of the TMS pulses was confirmed by simultaneous electromyographic monitoring of a hand muscle. Suprathreshold rTMS activated a network of primary and secondary cortical motor regions including M1/S1, supplementary motor area, dorsal premotor cortex, cingulate motor area, the putamen and thalamus. Subthreshold rTMS elicited no MRI-detectable activity in the stimulated M1/S1, but otherwise led to a similar activation pattern as obtained for suprathreshold stimulation though at reduced intensity. In addition, we observed activations within the auditory system, including the transverse and superior temporal gyrus, inferior colliculus and medial geniculate nucleus. The present findings support the notion that re-afferent feedback from evoked movements represents the dominant input to the motor system via M1 during suprathreshold stimulation. The BOLD MRI changes in motor areas distant from the site of subthreshold stimulation are likely to originate from altered synaptic transmissions due to induced excitability changes in M1/S1. They reflect the capability of rTMS to target both local and remote brain regions as tightly connected constituents of a cortical and subcortical network.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03277.x
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  • 6
    Digitale Medien
    Digitale Medien
    Characterization of the human visual V6 complex by functional magnetic resonance imaging (2003)
    Oxford, UK : Blackwell Science, Ltd
    European journal of neuroscience 17 (2003), S. 0 
    Details
    ISSN: 1460-9568
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Magnetoencephalography of a visual area along the human parieto-occipital sulcus suggested that this region represents the human homologue of the monkey visual area V6 complex (visual area V6/visuomotor area V6A) involved in the integration of visual and somatomotor information. We used functional magnetic resonance imaging at 2.0 T and 2 × 2 × 3 mm3 resolution (16 sections) to characterize visual areas along the parieto-occipital sulcus in five healthy human subjects. Paradigms comprised a full-field checkerboard stimulation, a full-field luminance flicker as well as a foveal and peripheral luminance flicker using both a direct and differential design for comparing functional states. Along the parieto-occipital sulcus, and in contrast to primary visual areas, luminance stimulation evoked much larger activation volumes than checkerboard stimulation. Moreover, based on anatomic landmarks, luminance stimulation identified two functionally distinct regions of parieto-occipital sulcus activations: an inferior part (supposedly visual area V6) and a superior portion (supposedly visuomotor area V6A). With these assignments, foveal vs. peripheral luminance stimulation revealed a weaker foveal overrepresentation in visual area V6/visuomotor area V6A than in early visual areas, and only a mild tendency for a retinotopic organization in visual area V6. Further analyses of the functional coding of the human visual area V6 complex require functional magnetic resonance imaging at even higher spatial resolution.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1460-9568.2003.02645.x
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  • 7
    Digitale Medien
    Digitale Medien
    Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes (2007)
    [s.l.] : Nature Publishing Group
    Nature genetics 39 (2007), S. 969-976 
    Details
    ISSN: 1546-1718
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Medizin
    Notizen: [Auszug] Oligodendrocytes myelinate axons for rapid impulse conduction and contribute to normal axonal functions in the central nervous system. In multiple sclerosis, demyelination is caused by autoimmune attacks, but the role of oligodendroglial cells in disease progression and axon degeneration is ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/ng2070
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  • 8
    Digitale Medien
    Digitale Medien
    Rapid FLASH NMR imaging (1987)
    Springer
    Naturwissenschaften 74 (1987), S. 415-422 
    Details
    ISSN: 1432-1904
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00446096
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  • 9
    Digitale Medien
    Digitale Medien
    High-resolution fast low-angle shot magnetic resonance imaging of the normal hand (1991)
    Springer
    Skeletal radiology 20 (1991), S. 259-265 
    Details
    ISSN: 1432-2161
    Schlagwort(e): Magnetic resonance (MR) imaging ; Joints, MR studies ; Wrist, MR studies ; Hand, MR studies ; Finger, MR studies ; Wrist anatomy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Cross-sectional magnetic resonance (MR) images of the normal hand, wrist, and fingers with an inplane resolution of 0.2–0.4 mm and a slice thickness of 1–2 mm were obtained using a 40-cm bore, 2.35-T MRI system equipped with actively shielded 50 mT m-1 gradient coils. A detailed description of the normal anatomy is given. The T1-weighted, multi-slice, fast low-angle shot (FLASH) MR images presented show a substantial improvement in resolution as compared with earlier reports. Typical investigational times of about 15 min offer a fast scan protocol that is suitable for routine clinical applications. The study further demonstrates the potential of dedicated magnets to facilitate and refine diagnostic MR imaging of hand injuries and hand-related diseases.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02341660
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  • 10
    Digitale Medien
    Digitale Medien
    Functional mapping of color processing by magnetic resonance imaging of responses to selective P- and M-pathway stimulation (1996)
    Springer
    Experimental brain research 110 (1996), S. 279-288 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Brain mapping ; Activation ; Functional, MRI ; Visual system ; Human
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Magnetic resonance imaging sensitized to activity-related changes in cerebral blood oxygenation was performed to map responses to selective stimulation of the parvo- and magnocellular visual pathways in calcarine and adjacent ventral occipital cortex of human subjects. In a repetitive stimulation protocol isoluminant chromatic or isochromatic luminance modulation was alternated with steady light of the same mean chromaticity and luminance as a reference condition. While no significant effects were observed for diffuse luminance modulation, two consistent cortical foci responded to isoluminant chromatic stimulation. A strong response was obtained in calcarine cortex at both 2 and 10 Hz, and even for selective S-cone stimulation. A second weaker colorsensitive response was seen bilaterally in the collateral sulcus. Thus, the data not only confirm color-sensitive activation in the collateral sulcus elicited in previous studies by selective cognitive tasks, but additionally demonstrate color-sensitive activation in primary visual cortex. With stimuli defined according to electrophysiological response properties of early visual processing stages, this study complements phenomenological or cognitive approaches in functional mapping of the human visual system.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00228558
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