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  • 1
    Digitale Medien
    Digitale Medien
    Boundary Migration Induced Plasticity during Recrystallization and Growth under Applied Stress (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 558-559 (Oct. 2007), p. 533-537 
    Details
    ISSN: 1662-9752
    Quelle: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Thema: Maschinenbau
    Notizen: In general, plastic strain occurs over a certain stress, called yield stress. However, it has beenreported that the permanent strain could happen during boundary migrating even under theextremely slight externally applied stress. In this study, we performed dilatometry experimentsunder the various compressive stresses and measured the amount of recrystallization and growthinduced permanent strain. A new empirical constitutive equation was suggested to describe therecrystallization and growth induced plasticity. This equation was verified by comparing thecalculated values with dilatometric experimental data under the various compressive stresses
    Materialart: Digitale Medien
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/17/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.558-559.533.pdf
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Analysis of the HLA-DRw8 haplotype: Recognition by HTC typing of three distinct antigen complexes in Caucasians, Native Americans, and Orientals (1983)
    Springer
    Immunogenetics 17 (1983), S. 399-410 
    Details
    ISSN: 1432-1211
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract We have used seven HLA-D homozygous typing cells (HTC) in a comparative study of the DRw8 antigen complex in three racial groups. Three distinct HLA-D specificities were recognized, each associated with HLA-DRw8. Four of the HTC defined a DRw8-associated HLA-D specificity designated 8.1, one defined a specificity designated 8.2, and two defined a specificity designated 8.3. Each of the three spec cities showed an association with a distinct racial group: Dw“8.1” in Caucasians, Dw“8.2” in Pacific Northwest Indians, and Dw“8.3” in Orientals. An informative primed lymphocyte (PLT) cell generated against a Dw“8.1” haplotype was able to distinguish 8.1 from 8.2 and 8.3. Using selected anti-DRw8 sera, a serologic distinction between 8.1 and 8.3 could also be made. It was thus possible, by using both cellular and serologic techniques in a comparative population study, to recognize at least three HLA-D-defined splits of the DRw8 haplotype.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00372458
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  • 3
    Digitale Medien
    Digitale Medien
    Differential behavior of cytotoxic effector cells against HLA antigens in strong genetic linkage disequilibrium (1981)
    Springer
    Immunogenetics 13 (1981), S. 297-309 
    Details
    ISSN: 1432-1211
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Five sets of cytotoxic effector cells were generated, using haploidentical, first degree relatives in five different families, against the HLA-A3; B7 serological determinants combined with different DR antigens. When tested against a panel of cells bearing combinations of the HLA-A, -B and -DR antigens it was shown that the HLA-B7 antigen was as strong a CML target determinant alone as it was in the presence of HLA-A3. The strength of the HLA-A3 antigen as target determinant varied. With effector cells primed to the HLA-A3; B7; DR2 haplotype, the A3 antigen alone behaved as a weak target determinant. When the same target cells were tested with the effector cells generated against HLA-A3; B7 without DR2, the A3 antigen behaved as a strong target determinant. A number of target cells lacking the serologically detectable HLA determinants present on the sensitizing HLA haplotype were identified as being killed by specific effector cells. These data suggest either a number of new CML target determinants controlled by different loci or the presence of a single, new locus with multiple alleles controlling CML targets.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00364495
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  • 4
    Digitale Medien
    Digitale Medien
    Diversity of the p70 Killer Cell Inhibitory Receptor (KIR3DL) Family Members in a Single Individual (2000)
    Springer
    Molecules and cells 10 (2000), S. 54-60 
    Details
    ISSN: 0219-1032
    Schlagwort(e): Alternative Splicing ; NK Cells ; p70 KIR ; Polymorphism ; Receptor Repertoire
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract NK cells and some T cells express members of a multigenic family of killer cell inhibitory receptors (KIRs) including p70 KIR (KIR3DL) and p58 KIR (KIR2DL) family that recognize polymorphic class I MHC molecules on target cells and transmit an inhibitory signal to prevent killer cell-mediated cytoxicity. The cDNA sequences of p70 KIR family members reported so far suggest that the p70 KIR gene consists of a multigene complex and that each gene may exhibit certain degrees of polymorphism. However, it is not clear how diverse the repertoire of the p70 KIR family is, particularly in a single individual. To address this question in more detail and to determine some indication as to the origin of the diversity, we cloned p70 KIR cDNAs from a single individual. We identified nine new KIRs that are different from the previously reported ones. A comparison of the amino acid sequences with published sequences of p70 KIRs showed that two clones belonged to the KIR3DL1 family, five clones belonged to the KIR3DL2 family, one clone belonged to the KIR2DL4 family, and one clone appeared to be an alternatively spliced form of p70 KIR. These results suggested that the repertoire of p70 KIR family members in a single individual is highly diverse. It is not clear how the diverse receptors are generated in a single individual, but a comparison of amino acid sequences of p70 KIR family members suggested that some of them may be encoded by distinct genes or their alleles, while others may be generated by a recombination mechanism and/or an alternative splicing mechanism at the maturation of the mRNA transcripts.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s10059-000-0054-0
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